A clinically annotated post-mortem approach to study multi-organ somatic mutational clonality in normal tissues

Recent research on normal human tissues identified omnipresent clones of cells, driven by somatic mutations known to be responsible for carcinogenesis (e.g., in TP53 or NOTCH1). These new insights are fundamentally changing current tumor evolution models, with broad oncological implications. Most st...

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Detalles Bibliográficos
Autores principales: Luijts, Tom, Elliott, Kerryn, Siaw, Joachim Tetteh, Van de Velde, Joris, Beyls, Elien, Claeys, Arne, Lammens, Tim, Larsson, Erik, Willaert, Wouter, Vral, Anne, Van den Eynden, Jimmy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209481/
https://www.ncbi.nlm.nih.gov/pubmed/35725896
http://dx.doi.org/10.1038/s41598-022-14240-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209481/
https://www.ncbi.nlm.nih.gov/pubmed/35725896
http://dx.doi.org/10.1038/s41598-022-14240-8

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