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A clinically annotated post-mortem approach to study multi-organ somatic mutational clonality in normal tissues
Recent research on normal human tissues identified omnipresent clones of cells, driven by somatic mutations known to be responsible for carcinogenesis (e.g., in TP53 or NOTCH1). These new insights are fundamentally changing current tumor evolution models, with broad oncological implications. Most st...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209481/ https://www.ncbi.nlm.nih.gov/pubmed/35725896 http://dx.doi.org/10.1038/s41598-022-14240-8 |