TADfit is a multivariate linear regression model for profiling hierarchical chromatin domains on replicate Hi-C data

Topologically associating domains (TADs) are fundamental building blocks of three dimensional genome, and organized into complex hierarchies. Identifying hierarchical TADs on Hi-C data helps to understand the relationship between genome architectures and gene regulation. Herein we propose TADfit, a...

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Detalles Bibliográficos
Autores principales: Liu, Erhu, Lyu, Hongqiang, Peng, Qinke, Liu, Yuan, Wang, Tian, Han, Jiuqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209495/
https://www.ncbi.nlm.nih.gov/pubmed/35725901
http://dx.doi.org/10.1038/s42003-022-03546-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209495/
https://www.ncbi.nlm.nih.gov/pubmed/35725901
http://dx.doi.org/10.1038/s42003-022-03546-y

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