Optimal CD8(+) T cell effector function requires costimulation-induced RNA-binding proteins that reprogram the transcript isoform landscape

Boosting T cell activation through costimulation directs defense against cancer and viral infections. Despite multiple studies targeting costimulation in clinical trials, the increased potency and reprogramming of T cells endowed by costimulation is poorly understood. Canonical dogma states that tra...

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Detalles Bibliográficos
Autores principales: Karginov, Timofey A., Ménoret, Antoine, Vella, Anthony T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209503/
https://www.ncbi.nlm.nih.gov/pubmed/35725727
http://dx.doi.org/10.1038/s41467-022-31228-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209503/
https://www.ncbi.nlm.nih.gov/pubmed/35725727
http://dx.doi.org/10.1038/s41467-022-31228-0

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