Satellite repeat transcripts modulate heterochromatin condensates and safeguard chromosome stability in mouse embryonic stem cells

Heterochromatin maintains genome integrity and function, and is organised into distinct nuclear domains. Some of these domains are proposed to form by phase separation through the accumulation of HP1ɑ. Mouse heterochromatin contains noncoding major satellite repeats (MSR), which are highly transcrib...

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Detalles Bibliográficos
Autores principales: Novo, Clara Lopes, Wong, Emily V., Hockings, Colin, Poudel, Chetan, Sheekey, Eleanor, Wiese, Meike, Okkenhaug, Hanneke, Boulton, Simon J., Basu, Srinjan, Walker, Simon, Kaminski Schierle, Gabriele S., Narlikar, Geeta J., Rugg-Gunn, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209518/
https://www.ncbi.nlm.nih.gov/pubmed/35725842
http://dx.doi.org/10.1038/s41467-022-31198-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209518/
https://www.ncbi.nlm.nih.gov/pubmed/35725842
http://dx.doi.org/10.1038/s41467-022-31198-3

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