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Rodent Modeling of Alzheimer's Disease in Down Syndrome: In vivo and ex vivo Approaches
There are an estimated 6 million people with Down syndrome (DS) worldwide. In developed countries, the vast majority of these individuals will develop Alzheimer's disease neuropathology characterized by the accumulation of amyloid-β (Aβ) plaques and tau neurofibrillary tangles within the brain,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209729/ https://www.ncbi.nlm.nih.gov/pubmed/35747206 http://dx.doi.org/10.3389/fnins.2022.909669 |