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Rodent Modeling of Alzheimer's Disease in Down Syndrome: In vivo and ex vivo Approaches

There are an estimated 6 million people with Down syndrome (DS) worldwide. In developed countries, the vast majority of these individuals will develop Alzheimer's disease neuropathology characterized by the accumulation of amyloid-β (Aβ) plaques and tau neurofibrillary tangles within the brain,...

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Detalles Bibliográficos
Autores principales: Farrell, Clíona, Mumford, Paige, Wiseman, Frances K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209729/
https://www.ncbi.nlm.nih.gov/pubmed/35747206
http://dx.doi.org/10.3389/fnins.2022.909669

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