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Dual Effects of Presynaptic Membrane Mimetics on α-Synuclein Amyloid Aggregation

Aggregation of intrinsically disordered α-synuclein (αSN) under various conditions is closely related to synucleinopathies. Although various biological membranes have shown to alter the structure and aggregation propensity of αSN, a thorough understanding of the molecular and mechanical mechanism of...

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Detalles Bibliográficos
Autores principales: Lin, Yuxi, Ito, Dai, Yoo, Je Min, Lim, Mi Hee, Yu, Wookyung, Kawata, Yasushi, Lee, Young-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209734/
https://www.ncbi.nlm.nih.gov/pubmed/35747692
http://dx.doi.org/10.3389/fcell.2022.707417