Extracellular Adenosine Triphosphate Binding to P2Y1 Receptors Prevents Glutamate-Induced Excitotoxicity: Involvement of Erk1/2 Signaling Pathway to Suppress Autophagy

Glutamate-induced neuroexcitotoxicity could be related to the pathophysiology of some neurodegenerative diseases including Parkinson’s disease and Alzheimer’s disease. Extracellular ATP exerts a wide variety of functions, such as attenuating Aβ-mediated toxicity, inhibiting N-Methyl-D-Aspartate (NMD...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiong, Yiping, Zhou, Duanyang, Zheng, Kai, Bi, Wenchuan, Dong, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209742/
https://www.ncbi.nlm.nih.gov/pubmed/35747207
http://dx.doi.org/10.3389/fnins.2022.901688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209742/
https://www.ncbi.nlm.nih.gov/pubmed/35747207
http://dx.doi.org/10.3389/fnins.2022.901688

Ejemplares similares