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Checkpoint activation drives global gene expression changes in Drosophila nuclear lamina mutants

The nuclear lamina (NL) lines the inner nuclear membrane. This extensive protein network organizes chromatin and contributes to the regulation of transcription, DNA replication, and repair. Lap2-emerin-MAN1 domain (LEM-D) proteins are key members of the NL, representing proteins that connect the NL...

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Detalles Bibliográficos
Autores principales: Kitzman, Samuel Cole, Duan, Tingting, Pufall, Miles A, Geyer, Pamela K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210273/
https://www.ncbi.nlm.nih.gov/pubmed/34893833
http://dx.doi.org/10.1093/g3journal/jkab408