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A sensitized genetic screen to identify regulators of Caenorhabditis elegans germline stem cells

GLP-1/Notch signaling and a downstream RNA regulatory network maintain germline stem cells in Caenorhabditis elegans. In mutants lacking the GLP-1 receptor, all germline stem cells enter the meiotic cell cycle precociously and differentiate into sperm. This dramatic germline stem cell defect is call...

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Detalles Bibliográficos
Autores principales: Robinson-Thiewes, Sarah, Kershner, Aaron M, Shin, Heaji, Haupt, Kimberly A, Kroll-Connor, Peggy, Kimble, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210287/
https://www.ncbi.nlm.nih.gov/pubmed/35100350
http://dx.doi.org/10.1093/g3journal/jkab439