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Generation of immunocompetent syngeneic allograft mouse models for pediatric diffuse midline glioma

BACKGROUND: Diffuse midline gliomas (DMG) are highly malignant incurable pediatric brain tumors. A lack of effective treatment options highlights the need to investigate novel therapeutic strategies. This includes the use of immunotherapy, which has shown promise in other hard-to-treat tumors. To fa...

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Detalles Bibliográficos
Autores principales: du Chatinier, Aimée, Meel, Michaël H, Das, Arvid I, Metselaar, Dennis S, Waranecki, Piotr, Bugiani, Marianna, Breur, Marjolein, Simonds, Erin F, Lu, Edbert D, Weiss, William A, Garcia Vallejo, Juan J, Hoving, Eelco W, Phoenix, Timothy N, Hulleman, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210310/
https://www.ncbi.nlm.nih.gov/pubmed/35733514
http://dx.doi.org/10.1093/noajnl/vdac079