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Random Peptides Rich in Small and Disorder-Promoting Amino Acids Are Less Likely to Be Harmful

Proteins are the workhorses of the cell, yet they carry great potential for harm via misfolding and aggregation. Despite the dangers, proteins are sometimes born de novo from noncoding DNA. Proteins are more likely to be born from noncoding regions that produce peptides that do little to no harm whe...

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Detalles Bibliográficos
Autores principales: Kosinski, Luke J, Aviles, Nathan R, Gomez, Kevin, Masel, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210321/
https://www.ncbi.nlm.nih.gov/pubmed/35668555
http://dx.doi.org/10.1093/gbe/evac085