Cargando…

Random Peptides Rich in Small and Disorder-Promoting Amino Acids Are Less Likely to Be Harmful

Proteins are the workhorses of the cell, yet they carry great potential for harm via misfolding and aggregation. Despite the dangers, proteins are sometimes born de novo from noncoding DNA. Proteins are more likely to be born from noncoding regions that produce peptides that do little to no harm whe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kosinski, Luke J, Aviles, Nathan R, Gomez, Kevin, Masel, Joanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210321/ https://www.ncbi.nlm.nih.gov/pubmed/35668555 http://dx.doi.org/10.1093/gbe/evac085

Ejemplares similares

Universal and taxon-specific trends in protein sequences as a function of age
por: James, Jennifer E, et al.
Publicado: (2021)

Wealth, health, and beyond: Is COVID-19 less likely to spread in rich neighborhoods?
por: Gong, Yue, et al.
Publicado: (2022)

Bisulfite Treatment of CG-Rich Track of Trinucleotide Repeat Expansion Disorder: Make the Sequence Less CG Rich
por: Joz Abbasalian, Zahra, et al.
Publicado: (2021)

The Recent De Novo Origin of Protein C-Termini
por: Andreatta, Matthew E., et al.
Publicado: (2015)

‘I perceive it to be less harmful, I have no idea if it is or not:’ a qualitative exploration of the harm perceptions of IQOS among adult users
por: East, Katherine A., et al.
Publicado: (2021)

Expanding the Landscape of Amino Acid-Rich Antimicrobial Peptides: Definition, Deployment in Nature, Implications for Peptide Design and Therapeutic Potential
por: Decker, Aaron P., et al.
Publicado: (2022)

Selective Recognition of Amino Acids and Peptides by Small Supramolecular Receptors
por: Martins, Joana N., et al.
Publicado: (2020)

Chemical Conjugation to Less Targeted Proteinogenic Amino Acids
por: Kjærsgaard, Nanna L., et al.
Publicado: (2022)

Peptide-Stabilized Emulsions and Gels from an Arginine-Rich Surfactant-like Peptide with Antimicrobial Activity
por: Castelletto, Valeria, et al.
Publicado: (2019)

Alternative Diagnosis Less Likely
por: Berdine, Gilbert, et al.
Publicado: (2021)

nQMaker: Estimating Time Nonreversible Amino Acid Substitution Models
por: Dang, Cuong Cao, et al.
Publicado: (2022)

Hydroxyl-Rich Hydrophilic Endocytosis-Promoting Peptide with No Positive Charge
por: Wang, Siwen, et al.
Publicado: (2022)

Less is More: Perception as a fun way to Rich Minimalism
por: Carbon, Claus-Christian, et al.
Publicado: (2022)

Metal-rich stars are less suitable for the evolution of life on their planets
por: Shapiro, Anna V., et al.
Publicado: (2023)

Small is Beautiful, Less is Better
por: Choi, Gun
Publicado: (2019)

Oxidative diversification of amino acids and peptides by small-molecule iron catalysis
por: Osberger, Thomas J., et al.
Publicado: (2016)

Small Fluorogenic Amino Acids for Peptide‐Guided Background‐Free Imaging
por: de Moliner, Fabio, et al.
Publicado: (2022)

A scoping review of implementation considerations for harm reduction vending machines
por: Russell, Erin, et al.
Publicado: (2023)

Less Experienced Telestroke Consultants Are More Likely to Go On-Camera, but Less Likely to Give tPA
por: de Havenon, Adam, et al.
Publicado: (2019)

Tryptophan-Rich and Proline-Rich Antimicrobial Peptides
por: Mishra, Awdhesh Kumar, et al.
Publicado: (2018)

Ginkgotides: Proline-Rich Hevein-Like Peptides from Gymnosperm Ginkgo biloba
por: Wong, Ka H., et al.
Publicado: (2016)

Vaccatides: Antifungal Glutamine-Rich Hevein-Like Peptides from Vaccaria hispanica
por: Wong, Ka H., et al.
Publicado: (2017)

Health warning labels describing snus as less harmful than smoking: effects on perceptions of risk
por: Nilsen, Connie Villemo, et al.
Publicado: (2020)

Q&A: Evolutionary capacitance
por: Masel, Joanna
Publicado: (2013)

Young Genes are Highly Disordered as Predicted by the Preadaptation Hypothesis of De Novo Gene Birth
por: Wilson, Benjamin A., et al.
Publicado: (2017)

Harmful somatic amino acid substitutions affect key pathways in cancers
por: Niroula, Abhishek, et al.
Publicado: (2015)

When self-harm is about preventing harm: emergency management of obsessive–compulsive disorder and associated self-harm
por: Palombini, Erika, et al.
Publicado: (2021)

Lung Deposition Analyses of Inhaled Toxic Aerosols in Conventional and Less Harmful Cigarette Smoke: A Review
por: Kleinstreuer, Clement, et al.
Publicado: (2013)

Brand Cigarillos — A Cheap and Less Harmful Alternative to Cigarettes? Particulate Matter Emissions Suggest Otherwise
por: Gerber, Alexander, et al.
Publicado: (2015)

Enteroendocrine-derived glucagon-like peptide-2 controls intestinal amino acid transport
por: Lee, Jennifer, et al.
Publicado: (2017)

l-Tyrosine Confers Residualizing Properties to a d-Amino Acid-Rich Residualizing Peptide for Radioiodination of Internalizing Antibodies
por: Lee, Fook T., et al.
Publicado: (2016)

The concept of “harm” in Internet gaming disorder
por: King, Daniel L., et al.
Publicado: (2018)

More or less likely to offend? Young adults with a history of identified developmental language disorders
por: Winstanley, Maxine, et al.
Publicado: (2017)

Little Fish Are Less Likely to Take the Bait
por: Marcovitch, Harvey
Publicado: (2005)

4‐Aminophthalimide Amino Acids as Small and Environment‐Sensitive Fluorescent Probes for Transmembrane Peptides
por: Wörner, Samantha, et al.
Publicado: (2019)

Younger Genes Are Less Likely to Be Essential than Older Genes, and Duplicates Are Less Likely to Be Essential than Singletons of the Same Age
por: Chen, Wei-Hua, et al.
Publicado: (2012)

Marketing ‘less harmful, low-tar’ cigarettes is a key strategy of the industry to counter tobacco control in China
por: Yang, Gonghuan
Publicado: (2014)

Existing trial data do not support that hydroxyethyl starch is less harmful when given on more ‘correct’ indications
por: Haase, Nicolai, et al.
Publicado: (2013)

A Pesticide Decision Support Tool to guide the selection of less environmentally harmful pesticides for the sugar cane industry
por: St. John Warne, Michael, et al.
Publicado: (2023)

Intercellular competition and the inevitability of multicellular aging
por: Nelson, Paul, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_j6ttllqs66ef2i8qq80cgnjsab