Hmga2 deficiency is associated with allometric growth retardation, infertility, and behavioral abnormalities in mice

The high mobility group AT-hook 2 (HMGA2) protein works as an architectural regulator by binding AT-rich DNA sequences to induce conformational changes affecting transcription. Genomic deletions disrupting HMGA2 coding sequences and flanking noncoding sequences cause dwarfism in mice and rabbits. He...

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Detalles Bibliográficos
Autores principales: Lee, Mi Ok, Li, Jingyi, Davis, Brian W, Upadhyay, Srijana, Al Muhisen, Hadil M, Suva, Larry J, Clement, Tracy M, Andersson, Leif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210324/
https://www.ncbi.nlm.nih.gov/pubmed/34878116
http://dx.doi.org/10.1093/g3journal/jkab417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210324/
https://www.ncbi.nlm.nih.gov/pubmed/34878116
http://dx.doi.org/10.1093/g3journal/jkab417

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