Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch

Chronic allergic itch is a common symptom affecting millions of people and animals, but its pathogenesis is not fully explained. Herein, we show that periostin, abundantly expressed in the skin of patients with atopic dermatitis (AD), induces itch in mice, dogs, and monkeys. We identify the integrin...

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Detalles Bibliográficos
Autores principales: Mishra, Santosh K., Wheeler, Joshua J., Pitake, Saumitra, Ding, Huiping, Jiang, Changyu, Fukuyama, Tomoki, Paps, Judy S., Ralph, Patrick, Coyne, Jacob, Parkington, Michelle, DeBrecht, Jennifer, Ehrhardt-Humbert, Lauren C., Cruse, Glenn P., Bäumer, Wolfgang, Ji, Ru-Rong, Ko, Mei-Chuan, Olivry, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210348/
https://www.ncbi.nlm.nih.gov/pubmed/32268102
http://dx.doi.org/10.1016/j.celrep.2020.03.036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210348/
https://www.ncbi.nlm.nih.gov/pubmed/32268102
http://dx.doi.org/10.1016/j.celrep.2020.03.036

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