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Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch
Chronic allergic itch is a common symptom affecting millions of people and animals, but its pathogenesis is not fully explained. Herein, we show that periostin, abundantly expressed in the skin of patients with atopic dermatitis (AD), induces itch in mice, dogs, and monkeys. We identify the integrin...
| Autores principales: | , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210348/ https://www.ncbi.nlm.nih.gov/pubmed/32268102 http://dx.doi.org/10.1016/j.celrep.2020.03.036 |