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Furosemide prevents membrane KCC2 downregulation during convulsant stimulation in the hippocampus

In adults, γ-aminobutyric acid (GABA) type A receptor (GABA(A)R)-mediated inhibition depends on the maintenance of low intracellular chloride anion concentration through neuron-specific potassium-chloride cotransporter-2 (KCC2). KCC2 has been widely reported to have a plasticity change during the co...

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Detalles Bibliográficos
Autores principales: Chen, Lulan, Yu, Jiangning, Wan, Li, Wu, Zheng, Wang, Guoxiang, Hu, Zihan, Ren, Liang, Zhou, Jing, Qian, Binbin, Zhao, Xuan, Zhang, Jinwei, Liu, Xu, Wang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210493/
https://www.ncbi.nlm.nih.gov/pubmed/35746976
http://dx.doi.org/10.1016/j.ibneur.2022.04.010