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Furosemide prevents membrane KCC2 downregulation during convulsant stimulation in the hippocampus
In adults, γ-aminobutyric acid (GABA) type A receptor (GABA(A)R)-mediated inhibition depends on the maintenance of low intracellular chloride anion concentration through neuron-specific potassium-chloride cotransporter-2 (KCC2). KCC2 has been widely reported to have a plasticity change during the co...
Autores principales: | Chen, Lulan, Yu, Jiangning, Wan, Li, Wu, Zheng, Wang, Guoxiang, Hu, Zihan, Ren, Liang, Zhou, Jing, Qian, Binbin, Zhao, Xuan, Zhang, Jinwei, Liu, Xu, Wang, Yun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210493/ https://www.ncbi.nlm.nih.gov/pubmed/35746976 http://dx.doi.org/10.1016/j.ibneur.2022.04.010 |
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