Neural circuit pathology driven by Shank3 mutation disrupts social behaviors

Dysfunctional sociability is a core symptom in autism spectrum disorder (ASD) that may arise from neural-network dysconnectivity between multiple brain regions. However, pathogenic neural-network mechanisms underlying social dysfunction are largely unknown. Here, we demonstrate that circuit-selectiv...

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Detalles Bibliográficos
Autores principales: Kim, Sunwhi, Kim, Yong-Eun, Song, Inuk, Ujihara, Yusuke, Kim, Namsoo, Jiang, Yong-Hui, Yin, Henry H., Lee, Tae-Ho, Kim, Il Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210496/
https://www.ncbi.nlm.nih.gov/pubmed/35675770
http://dx.doi.org/10.1016/j.celrep.2022.110906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210496/
https://www.ncbi.nlm.nih.gov/pubmed/35675770
http://dx.doi.org/10.1016/j.celrep.2022.110906

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