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Investigating the specificity of endothelin-traps as a potential therapeutic tool for endothelin-1 related disorders

BACKGROUND: Endothelin (ET)-traps are Fc-fusion proteins with a design based on the physiological receptors of ET-1. Previous work has shown that use of the selected ET-traps potently and significantly reduces different markers of diabetes pathology back to normal, non-disease levels. AIM: To demons...

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Detalles Bibliográficos
Autores principales: Jain, Arjun, Bozovicar, Kristof, Mehrotra, Vidhi, Bratkovic, Tomaz, Johnson, Martin H, Jha, Ira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210543/
https://www.ncbi.nlm.nih.gov/pubmed/35800412
http://dx.doi.org/10.4239/wjd.v13.i6.434