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Clarithromycin prevents preterm birth and neonatal mortality by dampening alarmin-induced maternal–fetal inflammation in mice

BACKGROUND: One of every four preterm neonates is born to a woman with sterile intra-amniotic inflammation (inflammatory process induced by alarmins); yet, this clinical condition still lacks treatment. Herein, we utilized an established murine model of sterile intra-amniotic inflammation induced by...

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Detalles Bibliográficos
Autores principales: Galaz, Jose, Romero, Roberto, Arenas-Hernandez, Marcia, Farias-Jofre, Marcelo, Motomura, Kenichiro, Liu, Zhenjie, Kawahara, Naoki, Demery-Poulos, Catherine, Liu, Tzu Ning, Padron, Justin, Panaitescu, Bogdan, Gomez-Lopez, Nardhy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210693/
https://www.ncbi.nlm.nih.gov/pubmed/35725425
http://dx.doi.org/10.1186/s12884-022-04764-2