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Secretion of miRNA-326-3p by senescent adipose exacerbates myocardial metabolism in diabetic mice

BACKGROUND: Adipose tissue homeostasis is at the heart of many metabolic syndromes such as diabetes. Previously it has been demonstrated that adipose tissues from diabetic patients are senescent but whether this contributes to diabetic cardiomyopathy (DCM) remains to be elucidated. METHODS: The stre...

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Detalles Bibliográficos
Autores principales: Lin, Hao, Chen, Xiaonan, Pan, Jianan, Ke, Jiahan, Zhang, Alian, Liu, Yangyang, Wang, Changqian, Chang, Alex Chia Yu, Gu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210699/
https://www.ncbi.nlm.nih.gov/pubmed/35729559
http://dx.doi.org/10.1186/s12967-022-03484-7