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Tideglusib promotes wound healing in aged skin by activating PI3K/Akt pathway

BACKGROUND: Aging disturbs the skin morphology and function, manifested as thinned epithelium and impaired wound healing. As a major type of skin cells, epidermal stem cells (EpiSCs) are inevitably affected by aging. The effect of age on EpiSCs and wound healing needs to be further explored. METHODS...

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Detalles Bibliográficos
Autores principales: Sun, Jiachen, Zhao, Hongqing, Shen, Chuan’an, Li, Shiyi, Zhang, Wen, Ma, Jinglong, Li, Zhisheng, Zhang, Ming, Yang, Jianqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210790/
https://www.ncbi.nlm.nih.gov/pubmed/35729652
http://dx.doi.org/10.1186/s13287-022-02949-2