Dnah9 mutant mice and organoid models recapitulate the clinical features of patients with PCD and provide an excellent platform for drug screening

Primary cilia dyskinesia (PCD) is a rare genetic disease caused by ciliary structural or functional defects. It causes severe outcomes in patients, including recurrent upper and lower airway infections, progressive lung failure, and randomization of heterotaxy. To date, although 50 genes have been s...

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Detalles Bibliográficos
Autores principales: Zheng, Rui, Yang, Wenhao, Wen, Yuting, Xie, Liang, Shi, Fang, Lu, Danli, Luo, Jiaxin, Li, Yan, Zhang, Rui, Chen, Ting, Chen, Lina, Xu, Wenming, Liu, Hanmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210797/
https://www.ncbi.nlm.nih.gov/pubmed/35729109
http://dx.doi.org/10.1038/s41419-022-05010-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210797/
https://www.ncbi.nlm.nih.gov/pubmed/35729109
http://dx.doi.org/10.1038/s41419-022-05010-5

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