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IL-1 and autoinflammatory disease: biology, pathogenesis and therapeutic targeting
Over 20 years ago, it was first proposed that autoinflammation underpins a handful of rare monogenic disorders characterized by recurrent fever and systemic inflammation. The subsequent identification of novel, causative genes directly led to a better understanding of how the innate immune system is...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210802/ https://www.ncbi.nlm.nih.gov/pubmed/35729334 http://dx.doi.org/10.1038/s41584-022-00797-1 |