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Targeting MDK Abrogates IFN-γ-Elicited Metastasis inCancers of Various Origins

IFN-γ is a pleiotropic cytokine with immunomodulatory and tumoricidal functions. It has been used as an anti-tumor agent in adjuvant therapies for various cancers. Paradoxically, recent advances have also demonstrated pro-tumorigenic effects of IFN-γ, especially in promoting cancer metastasis, with...

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Detalles Bibliográficos
Autores principales: Zheng, Luyu, Liu, Qun, Li, Ruijun, Chen, Shibin, Tan, Jingyu, Li, Lina, Dong, Xichen, Huang, Changzhi, Wen, Tao, Liu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210922/
https://www.ncbi.nlm.nih.gov/pubmed/35747815
http://dx.doi.org/10.3389/fonc.2022.885656