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Bioenergetic Failure Drives Functional Exhaustion of Monocytes in Acute-on-Chronic Liver Failure
OBJECTIVE: The monocyte–macrophage system is central to the host’s innate immune defense and in resolving injury. It is reported to be dysfunctional in acute-on-chronic liver failure (ACLF). The disease-associated alterations in ACLF monocytes are not fully understood. We investigated the mechanism...
Autores principales: | Maheshwari, Deepanshu, Kumar, Dhananjay, Jagdish, Rakesh Kumar, Nautiyal, Nidhi, Hidam, Ashinikumar, Kumari, Rekha, Sehgal, Rashi, Trehanpati, Nirupama, Baweja, Sukriti, Kumar, Guresh, Sinha, Swati, Bajpai, Meenu, Pamecha, Viniyendra, Bihari, Chhagan, Maiwall, Rakhi, Sarin, Shiv Kumar, Kumar, Anupam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210982/ https://www.ncbi.nlm.nih.gov/pubmed/35747140 http://dx.doi.org/10.3389/fimmu.2022.856587 |
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