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The cellular microenvironment and cytoskeletal actin dynamics in liver fibrogenesis

Hepatic stellate cells (HSCs) are the primary effector cells in liver fibrosis. In the normal liver, HSCs serve as the primary vitamin A storage cells in the body and retain a “quiescent” phenotype. However, after liver injury, they transdifferentiate to an “activated” myofibroblast-like phenotype,...

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Detalles Bibliográficos
Autores principales: HIJAZI, Nour, ROCKEY, Don C., SHI, Zengdun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9211003/
https://www.ncbi.nlm.nih.gov/pubmed/35734751
http://dx.doi.org/10.32604/biocell.2022.020171