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The cellular microenvironment and cytoskeletal actin dynamics in liver fibrogenesis
Hepatic stellate cells (HSCs) are the primary effector cells in liver fibrosis. In the normal liver, HSCs serve as the primary vitamin A storage cells in the body and retain a “quiescent” phenotype. However, after liver injury, they transdifferentiate to an “activated” myofibroblast-like phenotype,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9211003/ https://www.ncbi.nlm.nih.gov/pubmed/35734751 http://dx.doi.org/10.32604/biocell.2022.020171 |