Prophylactic (R,S)-Ketamine Is Effective Against Stress-Induced Behaviors in Adolescent but Not Aged Mice

BACKGROUND: (R,S)-ketamine, an N-methyl-D-aspartate receptor antagonist, is frequently used as an anesthetic and as a rapid-acting antidepressant. We and others have reported that (R,S)-ketamine is prophylactic against stress in adult mice but have yet to test its efficacy in adolescent or aged popu...

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Detalles Bibliográficos
Autores principales: Mastrodonato, Alessia, Pavlova, Ina, Kee, Noelle C, Pham, Van Anh, McGowan, Josephine C, Mann, J John, Denny, Christine A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Regular Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9211010/
https://www.ncbi.nlm.nih.gov/pubmed/35229871
http://dx.doi.org/10.1093/ijnp/pyac020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9211010/
https://www.ncbi.nlm.nih.gov/pubmed/35229871
http://dx.doi.org/10.1093/ijnp/pyac020

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