Plasma Levels of Tissue-Type Plasminogen Activator (tPA) in Normal Aging and Alzheimer's Disease: Links With Cognition, Brain Structure, Brain Function and Amyloid Burden

Tissue-type plasminogen activator (tPA) is a protease known for its fibrinolytic action but is also involved in physiological and pathophysiological aging processes; including amyloid elimination and synaptic plasticity. The aim of the study was to investigate the role of tPA in cognitive and brain...

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Detalles Bibliográficos
Autores principales: Tomadesso, Clémence, de Lizarrondo, Sara Martinez, Ali, Carine, Landeau, Brigitte, Mézenge, Florence, Perrotin, Audrey, de La Sayette, Vincent, Vivien, Denis, Chételat, Gaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9211060/
https://www.ncbi.nlm.nih.gov/pubmed/35747448
http://dx.doi.org/10.3389/fnagi.2022.871214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9211060/
https://www.ncbi.nlm.nih.gov/pubmed/35747448
http://dx.doi.org/10.3389/fnagi.2022.871214

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