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Comprehensive Analysis of Metabolic Changes in Male Mice Exposed to Sodium Valproate Based on GC-MS Analysis

PURPOSE: Sodium valproate (VPA) is the most widely used broad-spectrum antiepileptic first-line drug in clinical practice and is effective against various types of epilepsy. However, VPA can induce severe cardiotoxicity, nephrotoxicity, hepatotoxicity, and neurotoxicity, which limits its use. Metabo...

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Detalles Bibliográficos
Autores principales: Gao, Yahao, Jiang, Di, Wang, Changshui, An, Gang, Zhu, Li, Cui, Changmeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9211130/
https://www.ncbi.nlm.nih.gov/pubmed/35747443
http://dx.doi.org/10.2147/DDDT.S357530