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Gene Amplification of CYP51B: a New Mechanism of Resistance to Azole Compounds in Trichophyton indotineae

Trichophyton indotineae causes dermatophytosis that is resistant to terbinafine and azole compounds. The aim of this study was to determine the mechanisms of resistance to itraconazole (ITC) and voriconazole (VRC) in strains of T. indotineae. Two azole-sensitive strains (ITC MIC < 0.125 μg/mL; VR...

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Detalles Bibliográficos
Autores principales: Yamada, Tsuyoshi, Yaguchi, Takashi, Maeda, Mari, Alshahni, Mohamed Mahdi, Salamin, Karine, Guenova, Emmanuella, Feuermann, Marc, Monod, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9211412/
https://www.ncbi.nlm.nih.gov/pubmed/35546111
http://dx.doi.org/10.1128/aac.00059-22