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Deletion of cox7c Results in Pan-Azole Resistance in Aspergillus fumigatus

In Aspergillus fumigatus, the most prevalent resistance to azoles results from mutational modifications of the azole target protein Cyp51A, but there are non-cyp51A mutants resistant to azoles, and the mechanisms underlying the resistance of these strains remain to be explored. Here, we identified a...

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Detalles Bibliográficos
Autores principales: Chen, Mingcong, Zhong, Guowei, Wang, Sha, Chen, Peiying, Li, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9211413/
https://www.ncbi.nlm.nih.gov/pubmed/35647650
http://dx.doi.org/10.1128/aac.00151-22