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Lumasiran in the Management of Patients with Primary Hyperoxaluria Type 1: From Bench to Bedside

Primary hyperoxaluria (PH) is a rare genetic disease caused by excessive hepatic production and elevated urinary excretion of oxalate that leads to recurrent nephrolithiasis, nephrocalcinosis and, eventually, kidney failure. As glomerular filtration rate declines, oxalate accumulates leading to syst...

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Detalles Bibliográficos
Autores principales: D’Ambrosio, Viola, Ferraro, Pietro Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9211742/
https://www.ncbi.nlm.nih.gov/pubmed/35747094
http://dx.doi.org/10.2147/IJNRD.S293682