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Lumasiran in the Management of Patients with Primary Hyperoxaluria Type 1: From Bench to Bedside
Primary hyperoxaluria (PH) is a rare genetic disease caused by excessive hepatic production and elevated urinary excretion of oxalate that leads to recurrent nephrolithiasis, nephrocalcinosis and, eventually, kidney failure. As glomerular filtration rate declines, oxalate accumulates leading to syst...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9211742/ https://www.ncbi.nlm.nih.gov/pubmed/35747094 http://dx.doi.org/10.2147/IJNRD.S293682 |