Defining the substrate envelope of SARS-CoV-2 main protease to predict and avoid drug resistance

Coronaviruses can evolve and spread rapidly to cause severe disease morbidity and mortality, as exemplified by SARS-CoV-2 variants of the COVID-19 pandemic. Although currently available vaccines remain mostly effective against SARS-CoV-2 variants, additional treatment strategies are needed. Inhibito...

Descripción completa

Detalles Bibliográficos
Autores principales: Shaqra, Ala M., Zvornicanin, Sarah N., Huang, Qiu Yu J., Lockbaum, Gordon J., Knapp, Mark, Tandeske, Laura, Bakan, David T., Flynn, Julia, Bolon, Daniel N. A., Moquin, Stephanie, Dovala, Dustin, Kurt Yilmaz, Nese, Schiffer, Celia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9211792/
https://www.ncbi.nlm.nih.gov/pubmed/35729165
http://dx.doi.org/10.1038/s41467-022-31210-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9211792/
https://www.ncbi.nlm.nih.gov/pubmed/35729165
http://dx.doi.org/10.1038/s41467-022-31210-w

Ejemplares similares