Synovial joint cavitation initiates with microcavities in interzone and is coupled to skeletal flexion and elongation in developing mouse embryo limbs

The synovial cavity and its fluid are essential for joint function and lubrication, but their developmental biology remains largely obscure. Here, we analyzed E12.5 to E18.5 mouse embryo hindlimbs and discovered that cavitation initiates around E15.0 with emergence of multiple, discrete, µm-wide tis...

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Detalles Bibliográficos
Autores principales: Kim, Minwook, Koyama, Eiki, Saunders, Cheri M., Querido, William, Pleshko, Nancy, Pacifici, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212078/
https://www.ncbi.nlm.nih.gov/pubmed/35608281
http://dx.doi.org/10.1242/bio.059381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212078/
https://www.ncbi.nlm.nih.gov/pubmed/35608281
http://dx.doi.org/10.1242/bio.059381

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