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Fibroblast growth factor-9 expression in airway epithelial cells amplifies the type I interferon response and alters influenza A virus pathogenesis

Influenza A virus (IAV) preferentially infects conducting airway and alveolar epithelial cells in the lung. The outcome of these infections is impacted by the host response, including the production of various cytokines, chemokines, and growth factors. Fibroblast growth factor-9 (FGF9) is required f...

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Detalles Bibliográficos
Autores principales: Hiller, Bradley E., Yin, Yongjun, Perng, Yi-Chieh, de Araujo Castro, Ítalo, Fox, Lindsey E., Locke, Marissa C., Monte, Kristen J., López, Carolina B., Ornitz, David M., Lenschow, Deborah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212157/
https://www.ncbi.nlm.nih.gov/pubmed/35675358
http://dx.doi.org/10.1371/journal.ppat.1010228