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High generation of reactive oxygen species from neutrophils in patients with severe COVID-19

Neutrophilia and an elevated neutrophil:lymphocyte ratio are both characteristic features of severe COVID-19 infection. However, functional neutrophil responses have been poorly investigated in this setting. We utilised a novel PMA-based stimulation assay to determine neutrophil-derived reactive oxy...

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Detalles Bibliográficos
Autores principales: Veenith, Tonny, Martin, Helena, Le Breuilly, Martin, Whitehouse, Tony, Gao-Smith, Fang, Duggal, Niharika, Lord, Janet M., Mian, Rubina, Sarphie, David, Moss, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212205/
https://www.ncbi.nlm.nih.gov/pubmed/35729319
http://dx.doi.org/10.1038/s41598-022-13825-7