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S100A4 exerts robust mucosal adjuvant activity for co-administered antigens in mice

The lack of clinically applicable mucosal adjuvants is a major hurdle in designing effective mucosal vaccines. We hereby report that the calcium-binding protein S100A4, which regulates a wide range of biological functions, is a potent mucosal adjuvant in mice for co-administered antigens, including...

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Detalles Bibliográficos
Autores principales: Sen Chaudhuri, Arka, Yeh, Yu-Wen, Zewdie, Olifan, Li, Nga Shan, Sun, Jia-Bin, Jin, Tao, Wei, Bin, Holmgren, Jan, Xiang, Zou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212208/
https://www.ncbi.nlm.nih.gov/pubmed/35729204
http://dx.doi.org/10.1038/s41385-022-00535-6