Antiviral effect of phosphorothioate oligodeoxyribonucleotides complementary to human immunodeficiency virus

Modifications of oligodeoxyribonucleotides include the replacement of the backbone phosphodiester groups with phosphorothioate (S-ODNs) groups and the substitution of phosphorothioate (SO-ODNs) groups at both the 3′- and 5′-ends. In assays for HIV, oligomers (S-ODNs) were more active at the micromol...

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Detalles Bibliográficos
Autores principales: Kim, Sang-Gug, Hatta, Toshifumi, Tsukahara, Satoru, Nakashima, Hideki, Yamamoto, Naoki, Shoji, Yoko, Takai, Kazuyuki, Takaku, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 1995
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212667/
https://www.ncbi.nlm.nih.gov/pubmed/8612046
http://dx.doi.org/10.1016/0968-0896(94)00142-P

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212667/
https://www.ncbi.nlm.nih.gov/pubmed/8612046
http://dx.doi.org/10.1016/0968-0896(94)00142-P

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