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Early shedding of membrane-bounded ACE2 could be an indicator for disease severity in SARS-CoV-2

SARS-CoV-2 uses membrane bound Angiotensin-Converting Enzyme 2 (ACE2) as a key host receptor for its entry. However, inconsistent results are available in terms of shedding of membrane ACE2 and circulating levels of soluble ACE2 during SARS-CoV-2. To ascertain soluble ACE2 as an effective biomarker...

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Detalles Bibliográficos
Autores principales: Mariappan, Vignesh, Ranganadin, Pajanivel, Shanmugam, Lokesh, Rao, S.R., Balakrishna Pillai, Agieshkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. and Société Française de Biochimie et Biologie Moléculaire (SFBBM). 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212747/
https://www.ncbi.nlm.nih.gov/pubmed/35724946
http://dx.doi.org/10.1016/j.biochi.2022.06.005