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Receptor binding domain of SARS‐CoV‐2 from Wuhan strain to Omicron B.1.1.529 attributes increased affinity to variable structures of human ACE2

BACKGROUND: COVID-19 is an infectious disease declared as a global pandemic caused by SARS-CoV-2 virus. Genomic changes in the receptor binding domain (RBD) region of SARS‐CoV‐2 led to an increased, infectivity in humans through interaction with the angiotensin-converting enzyme2 (ACE2) receptor. Si...

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Detalles Bibliográficos
Autores principales: Patil, Shankargouda, Alzahrani, Khalid J., Banjer, Hamsa Jameel, Halawani, Ibrahim Faisal, Alzahrani, Hosam, Altayar, Malik A., Albogami, Sarah, Angeles, Robert Fua, Hassan, Ali Abdel-Halim Abdel-Azim, Bhandi, Shilpa, Raj, A. Thirumal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd on behalf of King Saud Bin Abdulaziz University for Health Sciences. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212875/
https://www.ncbi.nlm.nih.gov/pubmed/35738053
http://dx.doi.org/10.1016/j.jiph.2022.06.004