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SARS-CoV-2 infects an in vitro model of the human developing pancreas through endocytosis

Recent studies showed that SARS-CoV-2 can infect adult human pancreas and trigger pancreatic damage. Here, using human fetal pancreas samples and 3D differentiation of human pluripotent cells into pancreatic endocrine cells, we determined that SARS-CoV-2 receptors ACE2, TMPRSS2, and NRP1 are express...

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Detalles Bibliográficos
Autores principales: Szlachcic, Wojciech J., Dabrowska, Agnieszka, Milewska, Aleksandra, Ziojla, Natalia, Blaszczyk, Katarzyna, Barreto-Duran, Emilia, Sanak, Marek, Surmiak, Marcin, Owczarek, Katarzyna, Grzanka, Dariusz, Durzynska, Julia, Pyrc, Krzysztof, Borowiak, Malgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212970/
https://www.ncbi.nlm.nih.gov/pubmed/35756892
http://dx.doi.org/10.1016/j.isci.2022.104594