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An M protein coiled coil unfurls and exposes its hydrophobic core to capture LL-37
Surface-associated, coiled-coil M proteins of Streptococcus pyogenes (Strep A) disable human immunity through interaction with select proteins. However, coiled coils lack features typical of protein–protein interaction sites, and it is therefore challenging to understand how M proteins achieve speci...
Autores principales: | Kolesinski, Piotr, Wang, Kuei-Chen, Hirose, Yujiro, Nizet, Victor, Ghosh, Partho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212996/ https://www.ncbi.nlm.nih.gov/pubmed/35726694 http://dx.doi.org/10.7554/eLife.77989 |
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