MAF1, a repressor of RNA polymerase III-dependent transcription, regulates bone mass

MAF1, a key repressor of RNA polymerase (pol) III-mediated transcription, has been shown to promote mesoderm formation in vitro. Here, we show that MAF1 plays a critical role in regulating osteoblast differentiation and bone mass. Global deletion of MAF1 (Maf1(-/-) mice) produced a high bone mass ph...

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Detalles Bibliográficos
Autores principales: Phillips, Ellen, Ahmad, Naseer, Sun, Li, Iben, James, Walkey, Christopher J, Rusin, Aleksandra, Yuen, Tony, Rosen, Clifford J, Willis, Ian M, Zaidi, Mone, Johnson, Deborah L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212997/
https://www.ncbi.nlm.nih.gov/pubmed/35611941
http://dx.doi.org/10.7554/eLife.74740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212997/
https://www.ncbi.nlm.nih.gov/pubmed/35611941
http://dx.doi.org/10.7554/eLife.74740

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