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MAF1, a repressor of RNA polymerase III-dependent transcription, regulates bone mass

MAF1, a key repressor of RNA polymerase (pol) III-mediated transcription, has been shown to promote mesoderm formation in vitro. Here, we show that MAF1 plays a critical role in regulating osteoblast differentiation and bone mass. Global deletion of MAF1 (Maf1(-/-) mice) produced a high bone mass ph...

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Detalles Bibliográficos
Autores principales:	Phillips, Ellen, Ahmad, Naseer, Sun, Li, Iben, James, Walkey, Christopher J, Rusin, Aleksandra, Yuen, Tony, Rosen, Clifford J, Willis, Ian M, Zaidi, Mone, Johnson, Deborah L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212997/ https://www.ncbi.nlm.nih.gov/pubmed/35611941 http://dx.doi.org/10.7554/eLife.74740

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