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Intronic regulation of SARS-CoV-2 receptor (ACE2) expression mediated by immune signaling and oxidative stress pathways

The angiotensin-converting enzyme 2 (ACE2) protein is a key catalytic regulator of the renin-angiotensin system (RAS), involved in fluid homeostasis and blood pressure modulation. ACE2 also serves as a cell-surface receptor for some coronaviruses such as SARS-CoV and SARS-CoV-2. Improved characteriz...

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Detalles Bibliográficos
Autores principales: Richard, Daniel, Muthuirulan, Pushpanathan, Aguiar, Jennifer, Doxey, Andrew C., Banerjee, Arinjay, Mossman, Karen, Hirota, Jeremy, Capellini, Terence D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213013/
https://www.ncbi.nlm.nih.gov/pubmed/35756893
http://dx.doi.org/10.1016/j.isci.2022.104614